Santos Fustero was born in Aínsa, Spain, in 1949. He studied Chemistry at the University of Zaragoza, where he obtained his Licenciatura (equivalent to a B.Sc. degree) in Chemistry in 1972. He received his Ph.D. in Organic Chemistry in 1975 from the same University, working in the field of heterocyclic chemistry under the supervision of Prof J. Barluenga and Prof V. Gotor.

He spent two years as a post-doctoral research associate at Prof H. Lehmkuhl’s laboratory at Max-Planck-Institut für Kohlenforschung in Mülheim an der Ruhr, Germany, researching organometallic chemistry.

In 1983, he became Associate Professor at University of Oviedo, Spain, and in 1990, he was promoted to Full Professor in Organic Chemistry at University of Valencia.

In 2005, he also became research group leader at Centro de Investigación “Príncipe Felipe” (CIPF) in Valencia. His research interests include organofluorine and medicinal chemistry, fluorous synthesis, organocatalysis and new reaction methodologies.

Latest Publications

243. "Asymmetric Vinylogous Mukaiyama-Mannich Reactions of Heterocyclic Siloxy Dienes with Ellman's Fluorinated Aldimines"

Santos Fustero, Miriam Rodenes, Raquel Román, Daniel M. Sedgwick, Jose Enrique Aguado, Vadim A. Soloshonok, Jianlin Han, Haibo Mei, Mercedes Medio-Simon, Pablo Barrio

Adv. Synth. & Catal. 2019, accepted for publication (DOI 10.1002/adsc.201900464).

241. "Copper-Catalyzed Regioselective Synthesis of (E)-β-Fluorovinyl Sulfones"

Raquel Román, Natalia Mateu, Daniel M. Sedgwick, Santos Fustero.

Molecules 2019, 24(8), 1569 (Special Issue "Fabolous Fluorine in Organic and Medicinal Chemistry" ).

242. "Fluorine-Containing Drugs Approved by the FDA in 2018"

Haibo Mei, Jianlin Han, Raquel Román, Santos Fustero, Mercedes Medio-Simon, Daniel M. Sedgwick, Claudio Santi, Renzo Ruzziconi, Vadim A. Soloshonok.

Chem. Eur. J.  2019, 25, 2-25 (Review) DOI: 10.1002/chem.201901840.

240. "Chemodiscrimination of olefin bonds through cross-metathesis reactions; synthesis of functionalized β-lactam and β-amino acid derivatives"

Melinda Noon, Zsanett Benke, Santos Fustero, Ferenc Fülöp, Lorand Kiss

Eur. J. Org. Chem. 2019, 0000, accepted for publication.

239. "Vinyl Fluorides: Competent Olefinic Counterparts in the Intramolecular Pauson-Khand Reaction"

Raquel Román, Natalia Mateu, Ines López, Mercedes Medio-Simon, Pablo Barrio, Santos Fustero

Org. Lett. 2019, 21, 2569-2573.

238. "Chemistry of detrifluoroacetylatively in situ generated fluoro–enolates "
Haibo Mei, Jiang Liu, Santos Fustero, Raquel Román, Renzo Ruzziconi, Vadim A. Soloshonok, Jianlin Han.
Org. Biomol. Chem. 201917, 762-775

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Industry Collaborations

Asturpharma S.A.


Industrias AFRASA S.A.


Janssen Pharmaceutical Companies


Eli Lilly and Company




Santos Fustero Lardies

Universidad de Valencia

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